Hepatitis B Virus Nucleic Acid Test Result 1.87*10^5IU/ml requires medication. Hepatitis B virus nucleic acid test result 1.87e+05 represents 1.87*10^5IU/ml, which has exceeded the normal level and belongs to Hepatitis B virus DNA positive. Antiviral therapy needs to be initiated for people who are hepatitis B virus DNA positive if accompanied by a persistent elevation of ALT greater than one times the normal value, or if there is a family history of cirrhosis, cirrhosis, or hepatocellular carcinoma, or if there is fibrosis or inflammation of the liver on liver tissue examination. Commonly used antiviral drugs are nucleoside analogs, such as entecavir and tenofovir disoproxil fumarate, which have better safety and efficacy, but rare and seldom serious adverse reactions occur, such as renal insufficiency, rhabdomyolysis, and lactic acidosis. Hepatitis B virus nucleic acid test result of 1.87*10^5IU/ml needs to be seen in a regular hospital, complete the relevant examinations, and initiate antiviral treatment under the guidance of a specialized doctor.