Preterm babies drink less and less milk may be related to immature gastrointestinal development, improper feeding, disease and other factors, it is recommended to take a small amount of multiple feeding methods, master the correct feeding methods, and take the preterm babies to the doctor in a timely manner. 1. Gastrointestinal immaturity: preterm babies drink less and less milk is more and more immature gastrointestinal development, physiological structure is not perfect, it is recommended to change the way of feeding, take a small amount of feeding methods, and more observation. 2. Improper feeding: preterm babies drink less and less milk may also be related to improper daily feeding, such as feeding too often, feeding too much milk, etc., it is recommended that the mother to grasp the correct feeding method. 3. Disease: preterm babies drink less and less milk may also be related to diseases, such as indigestion, gastroesophageal reflux disease, congenital hypothyroidism and other diseases, the need to figure out the preterm baby’s body to the existence of diseases to be targeted treatment, such as indigestion can be changed to feed the way, more massage of preterm babies to help digestion of the abdomen, and drink some appropriate Bula yeast powder, and so on. Parents found that preterm babies drink less and less milk, should take the preterm babies to the regular hospital in a timely manner, by the doctor to guide the use of medication.