Fourth, the injury 1, acute spinal cord injury: acute spinal cord injury can cause death or permanent disability, seriously affecting the patient’s life safety and quality of life. The beneficial effect of hyperbaric oxygen therapy on spinal cord injury has been confirmed in animal experiments and clinical practice. Hyperbaric oxygen therapy is recommended as soon as possible after surgery; patients without surgical indications should be treated with hyperbaric oxygen therapy as soon as possible. The efficiency of hyperbaric oxygen therapy for spinal cord injury is 92.3%. 2, peripheral nerve injury: refers to some factors caused by nerve conduction dysfunction, nerve axon disruption or nerve rupture, resulting in trunk and limb sensory, motor, sympathetic dysfunction a class of clinical conditions. The efficiency of hyperbaric oxygen therapy for peripheral nerve injury can reach more than 90%. 3, squeeze injury and squeeze syndrome: manifested as swelling at the site of compression, sensory dullness or loss, motor disorders and myoglobinemia. Especially for acute carbon monoxide poisoning combined with extrusion syndrome, the efficiency of early hyperbaric oxygen therapy can reach more than 98%. 4, peripheral vascular disease: vasculitis, Raynaud’s disease, occlusive arteriosclerosis and other peripheral vascular diseases are also indications for hyperbaric oxygen therapy, hyperbaric oxygen can lift the embolism distal tissue hypoxia, to remove the redness of the affected limb, swelling inflammatory exudation, pain control have significant effects. It has been reported that the efficiency of hyperbaric oxygen combined with drug treatment for vasculitis is 95%.