This formula is used to treat jaundice caused by wind-cold superficial evil and damp-heat. This formula is used to treat jaundice caused by wind-cold superficial evil not yet dispersed and damp-heat accumulation. The combination of this formula is rigorous and well-matched, taking the internal treatment of damp-heat and the external dispersal of superficial evil, so that the superficial and internal evidence can be resolved in separate ways and each can be broken. Acute and chronic nephritis, nephrotic syndrome and other kidney diseases are classified as “edema”, “guan ge”, “long closure”, “deficiency labor” and “feng shui” in Chinese medicine. “The “wind and water”, “urinary turbidity”, “urine blood” and other categories, and edema is one of the most common symptoms of chronic kidney disease. It is stated in “The Essentials of the Golden Horoscope” that “the body is swollen when the wind and water fight each other, but it is cured by sweating”, indicating that the method of promoting lung sweating can treat edema, which coincides with the etiology and pathogenesis of chronic kidney disease. In recent years, we have used Ephedra forsythia and Chiaotou soup with reduction to treat various chronic kidney diseases, and have been repeatedly tested, so we will share with our colleagues. 1, treatment of IgA nephropathy Case 1 Du, male, 30 years old. Date of initial diagnosis: October 17, 2012. The patient has been diagnosed with IgA for 6 years, with long-term proteinuria and hematuria, 24 h protein quantification less than 1 g, no hypertension, and occasional morning eyelid edema. Intermittently taking nephritis rehabilitation tablets. In the last two weeks, he came to the hospital because he felt more foamy urine, fatigue, and eyelid swelling after having upper sensation, and the 24-h protein quantification was 1.53 grams. The rest of the symptoms were uneventful, with a red tongue with thin yellow coating and a smooth pulse. Blood pressure is 125/70 mmHg. Identification: Sun typhoid evidence. Treatment: Promoting the lung to stop cough, clearing heat and resolving phlegm; adding and subtracting three woose-tang with ephedra, forsythia, and red bean soup. Prescription: 15 g of water-baked ephedra, 12 g of almonds, 3 g of licorice, 12 g of ginger, 9 g of Chen Pi, 15 g of poria, 12 g of aster, 12 g of winter flowers, 9 g of burdock, 9 g of forsythia, 18 g of adzuki beans, 15 g of raw grain buds. taken morning and evening. Second consultation (October 24): cough stopped, urine routine showed urine protein (±), red blood cells (+), red tongue with clear coating and small string pulse. I gave Ginseng and Astragalus Dihuang Tang with silkworm cocoon shell 9 g, corn husk 15 g, thorny charcoal 12 g, small thistle 12 g, cyperus charcoal 12 g, scutellaria baicalensis 12 g, hebai grass 15 g. Third consultation (Nov 7): urine protein (+), red blood cells (+); fatigue, eyelid swelling; red tongue with thin yellow coating, small string pulse. Ginseng Ling Bai Zhu San with silkworm cocoon shell 9 g, corn husk 15 g, Jing Ji Charcoal 12 g, Xiao Thistle 12 g, Xi Cao Charcoal 12 g, Scutellaria Baicalensis 12 g, He Bai Cao 15 g. Fourth consultation (Nov 21): urine protein (+), red blood cells (++). The prescription was based on the first prescription of Ginseng and Atractylodes combined with Ephedra and Forsythia soup. Fifth consultation (Dec. 5): urine protein (-), red blood cells (3-5)/HP. no discomfort on complaint. The tongue is red with clear coating and the pulse is smooth. He was treated with this formula for a long time, and the 24-h protein quantification has been normal since the follow-up. According to IgA nephropathy, some people call it “sore throat nephritis”, and many people have long-term recurrent infections of the upper respiratory tract. In conventional treatment, heat is cleared and wind is removed during the infection period, while the spleen is strengthened and the kidney is tonified during the stabilization period. In this case, after clearing the heat and draining the wind due to an external infection, the spleen was strengthened and the kidney was tonified, but the effect was not good. Later on, Ephedra lianxiao and red bean soup was used in the remission period to stabilize the case. Proteinuria is similar to the concept of “essence qi”, “clear qi” and “essence micro” in Chinese medicine. In this case, the proteinuria is mostly related to kidney deficiency. The combination of kidney deficiency and the sensation of wind evil results in proteinuria. The chronic kidney disease caused by the external attack of wind evil, and the recurrence of proteinuria, which is manifested by a large amount of foam in the urine, is a typical manifestation of wind evil agitation. This is a typical manifestation of the wind evil agitation, which is called “wind energy flow agitation” by Ye Tianshi. There are also cases of urinary occult blood in people with normal urine routine. The “Treatise on the Origin of Diseases? Blood in the urine” says: “When the wind evil visits Shaoyin, blood in the urine”. The production of hematuria is also related to the wind evil, which penetrates the kidney membrane and the blood complex, and when the membrane complex is damaged and open to leakage, blood will seep out and develop into blood in urine. The wind evil has an important role in the production of hematuria in chronic nephritis. Thus, whether it is edema or proteinuria or hematuria in chronic nephritis, the treatment should be based on wind. The reason for this is that this formula is a good medicine to dispel wind. The Chinese medicine theory is that the throat is the marriage of the kidney, the throat is a pass, easy to commit external evil, Shaoyin kidney vein along the throat, holding the tongue, external evil invasion or from the respiratory tract and entry, coiled in the throat, stagnant, stasis poison; poison with the Shaoyin meridian down the kidney of the membrane, blood, leading to aggravation of the disease, difficult to relieve; kidney qi is damaged, the external guard is not solid, leading to the development of the disease, entanglement, forming a vicious circle of the throat and kidney. This is a good way to help the patient to get rid of the symptoms. 2, treatment of allergic purpura nephritis Case 2 Xu, female, 18 years old. Date of initial consultation: March 8, 2013. The patient developed allergic purpura for unknown reasons two years ago, which was stabilized by anti-allergic treatment. Six months ago, purpura reappeared after upper sensation with foamy urine. The 24-h protein quantification was 0.83 g. The liver and kidney functions were normal. The renal puncture showed focal segmental nephritis, which was treated with traditional Chinese medicine. She came to the clinic because her proteinuria was between 0.5 and 1 g for a long time and she had menstrual irregularities. She complained of delayed menstruation, decreased menstrual flow, and occasional stomach discomfort. The former doctor used blood cooling and heat-clearing agents, although the temporary effect was small, but not a long-term cure. The face is white, the voice is low, the breath is weak, the urine is white, the stool is loose, the tongue is light, the fur is white, the pulse is sunken and thin. Identification: spleen deficiency without transportation. Treatment: Strengthening the spleen and harmonizing the stomach. Prescription: Ginseng Ling Bai Zhu San plus 15 g of raw grain buds, to be taken morning and evening. Second consultation (March 15): urine protein (+), red blood cells (++). He complained that the color and aroma of the herbs were good and he was willing to continue to take the medicine, and the menstrual fluid would arrive next week. The tongue is light with thin white coating and the pulse is sunken and thin. The above prescription was supplemented with 12 g of Radix Aromaticus, 12 g of Radix Angelicae Sinensis and 6 g of Safflower. Third consultation (March 29): urine routine, urine protein (++), red blood cells (+); complained that the menstrual flow arrived as scheduled, with normal volume and color; the tongue was lightly coated and the pulse was sunken and thin. The prescription was based on Ginseng Fu and Atractylodes with 12 g of water roasted ephedra, 9 g of forsythia, 18 g of adzuki bean, 9 g of silkworm cocoon shell, 15 g of corn husk, 12 g of angelica, 12 g of made aromatic herb, 15 g of raw grain bud. Fourth consultation (April 12): urine protein (-), red blood cells (+); no special discomfort, light tongue with clear coating and smooth pulse. The previous prescription was supplemented with Dan Pi 9 g and Sha Ren 3 g. Fifth consultation (April 26): urine protein (-), erythrocytes (5-7)/HP. The original prescription was continued. Sixth consultation (May 10): 24 h protein quantification 0.05 g. Follow-up is stable for one year. According to Allergic purpura is a common immune disease, which is more common in preschool and school-age children, but can also be seen in adults. The “Surgery Zhengzong” has a description of “grape disease”: “Grape disease” is born in children, they feel the wrong qi in the four seasons, depressed in the skin does not dissipate, formed the size of blue and purple spots, color like grapes. This disease belongs to the category of hair spot, treatment is mostly to clear heat and detoxify, cool blood to stop bleeding method, choose rhinoceros horn Dihuang Tang, Hu Zhan Tang and so on, clinical although there is a small effect, but long-term use of health and loss of harmony, menstrual water extension. Therefore, such patients can be ginseng and white atractylodes and other formulas to strengthen the spleen and stomach, one is to establish its day, stabilize the condition, and the other can make the patient take the medicine after the stomach and stomach and smooth, compliance increased. At the same time, the author believes that, according to the manifestations of this disease, the spots develop on the skin, mostly overnight, and the spots have an itching sensation at the beginning, which are very similar to the characteristics of “wind evil”. Therefore, the treatment of this disease with the addition and subtraction of Ephedra, forsythia, and red bean soup is often effective, and it will not affect the transportation of the middle jiao and menstruation of women due to too much cold, so the treatment is stable. 3. Conclusion The understanding of the formula of Ma Huang Lian Qiao Qi Qi Qi Xiao Dou Tang by successive generations of physicians varies. Most physicians consider it to be a variation of Ephedra Tang, for example, Ke Yunbai of the Qing Dynasty said, “This soup is a variation of Ephedra Tang as well.” Fan Rongqiang believes that this formula is an addition or subtraction of the combination of Ephedra Tang and Yue Maida Tang. According to Chen Ming, Ma Huang Lian Qiao Chi Xiao Dou Tang is a variation of Ma Heng Shi Gan Tang, which treats lung-heat, except that it treats damp-heat. In this formula, ephedra is used to open up the lung, so that the evil is removed from the surface; together with forsythia and red bean, it clears heat and dampness; mulberry bark clears heat and water and promotes lung qi, so that the evil of dampness and heat is removed from the urine; ginger and jujube protect the stomach qi, so that the spleen and earth are healthy and have the main control of water. The whole formula works together to promote the function of dispersing evil, clearing heat and promoting water. Ephedra with forsythia and red bean soup is widely used clinically for many common kidney diseases. Although this formula is a classic formula for treating damp-heat jaundice in the Treatise on Typhoid, it is nowadays more often used in the treatment of acute and chronic kidney diseases to slow down the progression of chronic kidney diseases. For example, nephritis edema, acute nephritis, nephrotic syndrome, allergic purpura as well as purpura kidney, acute pyelonephritis, lupus kidney, chronic nephritis after massive hormone combined with skin infection, hepatorenal syndrome, etc. Its effect may be related to the anti-inflammatory properties of ephedra and improvement of immune function of patients. Of course, its anti-inflammatory mechanism, immunosuppression and other related mechanisms need to be further explored in clinical and animal experiments.