Scratching chronic urticaria is mainly a skin scratching sign. It is characterized by the appearance of striated, edematous erythema after scratching, which can subside on its own after a few seconds. It can be treated by taking 1 oral tablet of Avastin 3 times a day, combined with Olopatadine hydrochloride tablets, 1 tablet in the morning and 1 tablet in the evening, and by applying glyburide lotion. In the process of treatment, it is best to find the cause of the disease, if it is caused by infection, such as Helicobacter pylori infection, oral anti-infective drugs are required for treatment; for hives caused by allergic factors, it is necessary to find the appropriate allergens, including dust mites, dust mites, dust, beef, mutton, eggs, milk, and durian, mango-type fruits. Once found, attention and avoidance can be paid to the root of the treatment.