1.Abnormal hormone secretion syndrome: excessive hormone secretion syndrome, such as growth hormone excess caused by telangiectasia; hormone secretion syndrome, when the non-functional tumor increases in size and normal pituitary tissues are destroyed, gonadotropin secretion is reduced, and amenorrhea, infertility or impotence occurs at the earliest time and it is very common. 2.Tumor compression of peripituitary tissues: nerve fiber irritation, headache, persistent headache; optic nerve, optic cross and optic nerve bundle compression, patients with vision loss, visual field defects and fundus changes; other compression syndromes.