The time needed to develop from renal atrophy to uremia is mainly related to the treatment of the patient’s primary disease and daily living habits, etc., and cannot be generalized. Renal atrophy usually refers to the phenomenon of kidney volume reduction and physiological function reduction. Uremia is a condition in which the kidney disease progresses to the end stage and needs to be treated with dialysis. Normally, both kidneys are atrophied to cause uremia, while unilateral kidney atrophy, because there is one kidney with kidney function, so uremia will not occur. For patients with kidney atrophy who are treated well and have a regular daily life, they may develop uremia in 2-3 years or even longer. In contrast, for patients who do not actively cooperate with treatment and have an irregular life, it may take only a few months. In addition, patients with renal atrophy are advised to avoid strain, low-fat, low-salt, low-protein diet, avoid taking nephrotoxic drugs, and actively delay the progression of chronic kidney disease under the guidance of a specialist.