Lupus erythematosus combined with nephrotic syndrome may suggest lupus nephritis, which requires renal biopsy to further define the type of pathology, and treatment with glucocorticoids, merti-macrolide, hydroxychloroquine and other drugs as prescribed by the doctor.
Systemic lupus erythematosus (SLE) is an autoimmune disease with multi-system involvement of undetermined etiology. About 75% of patients present with renal involvement such as abnormal urinalysis and/or abnormal renal function, which is called lupus nephritis. If a renal biopsy is performed, the percentage of renal involvement is even higher. Lupus erythematosus combined with nephrotic syndrome suggests renal puncture biopsy to clarify the type of pathology and timely treatment.
1. Immunosuppressants: including glucocorticoids, cyclophosphamide, mertiomacrophenol, azathioprine, neurocalcitonin inhibitors such as cyclosporine and tacrolimus, leflunomide.
2. Other treatments: including plasma exchange, intravenous immunoglobulin, rituximab, etc.
3. Other synergistic treatments: including hydroxychloroquine, proteinuria-lowering treatment, anti-hypertension, lipid-lowering, etc.
Lupus erythematosus combined with nephrotic syndrome should go to the hospital in time and be treated under the guidance of professional doctors. Drugs should be used according to the doctor’s prescription, do not self-medicate.