Y chromosome microdeletion, which prevents normal fertility. Patients often have symptoms of oligospermia or azoospermia, and cannot conceive normally, nor can they be effectively treated by medication, but they can achieve fertility through IVF and other means of fertility assistance. It is recommended to visit the fertility department of the hospital in time and choose the appropriate treatment method by referring to the doctor’s opinion through relevant examinations. Through IVF technology, embryos are screened for transfer to exclude embryos with Y chromosome microdeletion to avoid the birth of babies with Y chromosome microdeletion.