Patients with high glutamate can be treated with cholestatic, hepatoprotective and hepatoprotective therapy, such as reduced glutathione and cholestrol capsules, etc. It is important to clarify the cause of the disease through examination and provide targeted treatment. If it is caused by alcohol consumption, the patient should stop drinking; if it is caused by virus, antiviral treatment is needed; if it is caused by drug damage, bad drugs should be stopped. Glutamate is an important indicator of liver function. Viral hepatitis, drug-related liver damage or obstructive jaundice can lead to significantly elevated glutamate. More commonly there is a close relationship with alcohol consumption, especially glutamate dehydrogenase, an enzyme that detoxifies alcohol, and in the course of long-term alcohol consumption or abuse, patients can develop a significant increase in glutamate. Patients should detect early what kind of abnormalities in liver function, and determine whether the liver shows acute bruising, acute enlargement, or even cirrhosis through a series of liver disease enzymology and bilirubin tests, as well as ultrasound, CT, and other imaging tests.