Differential diagnosis of fine granular tubular urine

  Under certain conditions, proteins filtered out by the kidneys as well as cells or debris coagulated in the renal tubules (distal bend) and collecting ducts can form cylindrical protein aggregates and be excreted with the urine, called tubular. Fine granular tubular urine is defined as containing more fine, sparse particles. Fine grain tubular urine needs to be diagnosed differently from the following types of tubular urine.  1, transparent tubular urine is a colorless and uniform translucent cylinder. 27% of normal people can have transparent tubular urine, which is of little clinical significance. It can be seen in the urine during strenuous exercise, kidney stimulation and ether anesthesia.  2, leukocyte tubular urine tubular white blood cells or pus balls in a roller arrangement, suggesting the presence of acute and chronic pyelonephritis, acute pyelonephritis is often accompanied by bacterial tubular pattern. Leukocyte tubular pattern can also be seen in non-renal substantive infectious diseases, such as streptococcal infectious nephritis, membranoproliferative nephritis and active lupus nephritis.  3, erythrocyte tubular urine refers to the tubular pattern containing multiple red blood cells. When the red blood cells are lysed into red-brown particles, it is called blood tubular. Both erythrocyte tubular pattern and blood tubular pattern suggest intrarenal hemorrhage, which can be seen in acute and chronic glomerulonephritis, acute tubular necrosis, renal infarction, and renal transplant rejection reaction.