Knee joint irrigation is suitable for knee joint inflammation (such as bursitis) and so on, generally will not aggravate the condition, but individual patients may cause insufficient secretion of knee joint fluid after repeated irrigation, and may also be heavy condition. The knee joint cavity is a closed negative pressure cavity, the knee joint tissue has the function of secretion of joint fluid, there is a certain degree of lubrication of the joint, the negative pressure cavity microenvironment is in a state of dynamic equilibrium. If this dynamic balance is disrupted after repeated knee joint irrigation due to knee joint pathologies such as bursitis and knee cysts, this may cause insufficient joint fluid secretion. As the knee joint secretes less fluid, the joint movement becomes astringent, so the pain may also worsen, limiting the range of motion. Therefore, if knee flushing perfusion interferes with the normal endocrine fluid function of the knee joint cavity, the condition may be aggravated. If there is an aggravation of the condition after treatment, it is recommended to go to the hospital for regular treatment under the guidance of a doctor.