Waking up with a sore throat in the morning may be caused by a dry environment, chronic pharyngitis, reflux pharyngitis and other reasons. 1. Dry environment: If the indoor environment of sleeping at night is dry and the indoor humidity is not enough, it may lead to the situation of waking up with a sore throat in the morning. 2. Chronic pharyngitis: Chronic pharyngitis is a chronic inflammation of the pharyngeal mucosa, submucosa, and lymphatic tissue. Patients with chronic inflammation, chronic congestion, and chronic infection in the pharynx will experience symptoms of waking up with a sore throat in the morning. 3. Reflux pharyngitis: At night when you sleep, stomach acid refluxes into the throat area, causing irritation to the throat and causing a sore throat in the morning. Waking up with a sore throat in the morning may also be caused by rhinitis, sinusitis, nasal polyps and other nasal congestion, you can actively go to the hospital, after a systematic examination to clarify the diagnosis and cause of the disease.