Pancreatic cancer is located on the left side of the upper abdomen and is broadly divided into pancreatic head cancer, pancreatic body cancer and pancreatic tail cancer. The early symptoms of pancreatic cancer are not obvious, but there are three prominent symptoms: (1) anorexia, indigestion and weight loss; (2) abdominal discomfort or pain, about half of the patients have abdominal pain as the first symptom, about 20% of the patients have abdominal pain radiating to the back and left shoulder, the pain increases when lying on the back and decreases when sitting, standing, bending, lying on the side or bending the knees; (3) jaundice, manifested as yellowing of the skin and sclera. The above symptoms can also appear in the case of hepatitis or biliary tract disease, so it is not uncommon for early pancreatic cancer to be misdiagnosed as hepatitis or cholecystitis or cholelithiasis. Pancreatic head cancer is most likely to cause jaundice, liver enlargement, and light-colored stools with white clay-like appearance because it tends to compress the common bile duct and block bile drainage, causing bile to leak into the blood. Therefore, pancreatic head cancer is relatively more likely to be detected at an early stage. The symptoms of pancreatic body cancer are mainly painful because the pancreatic body is adjacent to the abdominal nerve plexus, and the lesion can easily invade the nerves, and the pain is intermittent or persistent and worsens at night. The symptoms of pancreatic tail cancer are more insidious and pain is not common. In addition to general wasting, weakness, food celebration and dyspepsia, sometimes it is manifested as a mass in the left upper abdomen, which can be easily misdiagnosed as left kidney disease. Since it is not easily detected in time, only 10%-25% of patients diagnosed with pancreatic cancer can be considered for surgery and the cure rate is very low, so early diagnosis is very important. It is generally believed that the following clinical manifestations should be taken seriously in patients over 40 years old: (1) progressive obstructive jaundice; (2) unexplained intractable epigastric pain and low back pain; (3) unexplained weight loss; (4) steatorrhea (caused by inadequate pancreatic fluid secretion and poor fat digestion); (5) diabetes mellitus (symptomatic diabetes due to destruction of pancreatic islet cells).