(Disclaimer: This article is for general use only, and the following information has been processed to protect patient privacy) Abstract: Acute hepatitis B differs from chronic hepatitis B in that it is a DNA infection with a high cure rate, and most viruses can be completely cleared. As in this case, a 56-year-old woman came to the hospital with the complaints of “yellow urine for more than 10 days and abdominal distension for 8 days” and had taken oral medication on her own to no avail. After physical examination and relevant auxiliary tests, the patient was finally diagnosed with acute hepatitis B. After standardized treatment, the patient was clinically treated. After standardized treatment, the patient’s clinical symptoms disappeared, liver function improved, and the disease was cured. [Basic information] Female, 56 years old [Disease type] Acute hepatitis B [Hospital] Liaoning Provincial People’s Hospital [Consultation time] April 2019 [Treatment plan] Intravenous infusion (polyenyl phosphatidylcholine injection, magnesium isoglycyrrhizate injection, thin glucose peptide injection) + oral medication (gardenia yellow granules) [Treatment cycle] Hospitalization for 5 days, regular outpatient follow-up [Treatment effect] Clinical symptoms The clinical symptoms disappeared, the liver function improved, and the disease was cured. The patient reported that she developed yellow urine more than 10 days ago without fever, frequent, urgent and painful urination, and started to have abdominal distension 8 days ago, which was obvious after eating, accompanied by loss of appetite, nausea, erratic, no vomiting, no acid reflux and heartburn, and oral anti-inflammatory drugs for 2 days without effect. He had a history of cerebral infarction 5 years ago. He had a history of cerebral infarction 5 years ago. After questioning and consultation, the initial diagnosis was “acute viral hepatitis B (jaundice)”. The patient and his family requested hospitalization, so he was admitted to the ward. The patient was given secondary care in the infection department, blood-fluid isolation, and bed rest. The patient’s case was characterized as a middle-aged female with an acute onset, characterized by “gastrointestinal symptoms with jaundice” and markedly abnormal liver function, consistent with acute viral hepatitis. The serum test was completed and the results indicated that the patient was positive for hepatitis B surface antigen and hepatitis B e antigen (see figure), but the surface antigen titer was not high, and the hepatitis B virus was replicating, but the replication amount was not large. The patient was given polyene-phosphatidylcholine injection and magnesium isoglycyrrhizinate injection as sedative, liver-protecting and enzyme-lowering treatment; Injasmine yellow granules were taken orally to remove yellowing; Bozhi glycopeptide injection was given as sedative to enhance immunity. Because of acute hepatitis, the possibility of hepatitis B virus clearing by itself is very large, so antiviral treatment is not temporarily. The patient was hospitalized for 5 days, and the effect of symptomatic treatment such as liver protection, enzyme lowering and yellowing elimination was remarkable, the patient’s abdominal distension improved significantly and his appetite was enhanced. The patient’s abdominal distension improved significantly, and his appetite increased. The patient was allowed to be discharged after the liver function improved significantly and the jaundice was reduced. One year after discharge, the patient came to our hospital for a review of the five hepatitis B tests and found that the hepatitis B surface antigen was cleared and the hepatitis B surface antibody was produced, indicating that the patient was cured of acute hepatitis B. I am sincerely happy that the patient’s condition has been cured, but the patient is still infectious because the hepatitis B virus has not yet been cleared and there is still a small amount of virus replication in the body at the time of discharge, but do not be overly nervous, the hepatitis B virus cannot be transmitted through the digestive tract and respiratory tract, so common dining and daily contact cannot infect others. Remind patients of the need to pay attention to rest in daily life, appropriate exercise, enhance immunity, diet to give patients light, highly nutritious, easy to digest and absorb food, pay attention to the intake of protein and vitamins to help enhance physical fitness. V. Personal insight The chronicity of hepatitis B has a lot to do with the patient’s age, immunity, genetic factors, such as when the body is in hypersensitivity reaction, under the action of various cytokines, can lead to a large area of hepatocyte necrosis and the occurrence of heavy hepatitis. Fortunately, this patient was able to completely clear the virus after standard treatment. It is clinically estimated that about 10% of patients with acute hepatitis B turn into chronic hepatitis B. Therefore, early detection, diagnosis and treatment of acute hepatitis B is crucial after the appearance of related symptoms.