The most common treatment for severe symptoms of cholecystitis, gallbladder stones and gallbladder polyps is cholecystectomy, which includes both laparoscopic and open cholecystectomy methods. Regardless of the method, there are always some psychological concerns left for patients, such as, “Does the removal of the gallbladder have a big impact on eating”, “How can I digest food when the gall is gone”, and there are many targeted solutions for patients faced by hepatobiliary surgeons in clinical practice. How big is the impact on the body? Evaluate the impact of a treatment method on the body from two perspectives: immediate and long-term effects, so what are the immediate effects of cholecystectomy? Take the laparoscopic cholecystectomy patients, the front-line clinical doctors have a deeper understanding of this, because patients with postoperative discomfort will mostly go back to the surgeon for treatment, according to our observation, about a quarter of the general post-cholecystectomy patients have a slight feeling of distension after meals within two weeks, but these symptoms will gradually disappear in about a month. Of course, there are a few patients who reported occasional pins and needles in the right upper abdomen even a few months after surgery. I think this may be related to the slight adhesion and pulling of the gallbladder bed and abdominal wall or intestinal canal, which is not harmful and does not require medication or injection. What is the role of the gallbladder? This is what patients are most concerned about before the gallbladder is cut. They think that the gallbladder has the function of digesting food and secreting bile, so naturally, without gallbladder, the digestive function is half shorter than others. In fact, to use an analogy, the gallbladder is equivalent to a small pond next to a reservoir, which can be filled with water to cushion the pressure of the reservoir’s capacity, and filling the pond with soil will not significantly affect the reservoir. Bile is secreted by the liver, the gallbladder only plays the role of temporary storage of bile, in turn the gallbladder plays the role of regulating bile secretion, after the removal of the gallbladder, its role will be replaced by the common bile duct, there is no problem of missing the role. What are the long term effects of gallbladder removal on the body? Some experts point out that it may produce peptic ulcers or increase the prevalence of colon cancer, but there is no unified conclusion in the academic field, because there is no strict statistical data to show the validity of this view. Long-term follow-up of patients who underwent cholecystectomy for gallbladder disease showed a significant improvement in quality of life, and in the long run, the benefits of resection far outweighed the benefits of not having it. Excision for gallbladder stones eliminates the risk of gallbladder stones becoming bile duct stones, and excision for multiple polyps or large polyps removes the risk of gallbladder cancer.