Median cells account for 50%-70% of the total leukocyte count in the peripheral blood, with a normal range of 2000-7000/mL, and more than 7000/mL is an increased median cell count. Increased median cell count is common in acute infections such as acute suppurative tonsillitis, acute suppurative appendicitis, etc. Also, high median cell count can occur in severe tissue injury, such as after severe trauma or major surgery. In addition, severe toxicity, such as diabetic ketoacidosis and uremic syndrome, can also result in a high median cell count. The most common causes of low median cell count are viral infections such as cold and flu, rubella virus, etc. Also, bone marrow hypopoietic disorders such as aplastic anemia can also cause a decrease in median cell count.