Condyloma acuminata (condyioma acuminata), also known as acromegaly, genital warts, and venereal warts. They are epidermolysis bullosa-like growths on the genitals, perineum, and anus (a few occur in the armpits, breasts, mouth, ears, and oral cavity) caused by human papilloma virus (HPV) infection. It is one of the most common sexually transmitted diseases worldwide. Recurrent attacks are one of the characteristics of the disease, especially intra-urethral and urethral condyloma acuminata are clinically difficult to treat. In the past, ordinary laser treatment and surgery were generally used, but the treatment was painful for patients, easy to recur after treatment, damaging to sexual organs, slow recovery, and causing urethral scarring, urethral adhesions, leading to urethral stricture. In contrast, ALA-PDT therapy has achieved satisfactory results in the treatment of intraurethral condyloma acuminata. Photodynamic therapy, PDT therapy, referred to as ALA-PDT, is a new technology that combines the application of photosensitizers and corresponding light sources to selectively destroy diseased tissue by inserting therapeutic optical fibers into the urethra through photochemical reactions. It is the ideal clinical solution for the treatment of urethral warts, especially for the treatment of urethral warts. The treatment does not require anesthesia and is painless. 3.Low recurrence rate: HPV subclinical infection and latent lesions can be treated at the same time, significantly reducing the recurrence rate. 4, can be used in the urethra, urethral orifice, and female cervical area condyloma acuminatum treatment.