Patients with very painful kidney stones can be relieved by the following ways: 1, can be relieved by oral medication, oral analgesic fenbid, combined with stone removal drugs such as stone removal particles and urinary stone pass, etc., through the pain and promote the discharge of stones, so as to achieve the effect of relieving kidney stone pain; 2, can choose intramuscular injection of 654-2 to relieve ureteral spasm, intramuscular injection of progesterone to promote stone removal, anal external use of 3, if necessary, extracorporeal shock wave lithotripsy and minimally invasive surgery for treatment, mainly applied when drug treatment is not effective; 4, if the application of pain medication is not effective, and not suitable for lithotripsy treatment, you can choose to leave the ureteral stent tube, or renal pelvic aspiration drainage to relieve pain. The above methods can be used to relieve the pain of kidney stones in patients, and the specific choice of treatment should be made under the guidance of a doctor.