Headache is a normal physiological phenomenon, not a pathological phenomenon. Patients will have headache due to reduced sleep time, when the brain and nerves do not get sufficient rest and the symptoms of brain ischemia and lack of oxygen. It is recommended that patients should have regular rest and not stay up late. Staying up late will not only cause headache but also lower the body’s resistance and increase the chance of tumor. Headaches caused by staying up late are mostly neurovascular headaches, and patients can take oral medication, such as blood and brain clearing pellets or headache capsules, or oral pain relief medication such as ibuprofen tablets or Loxone tablets for treatment.