Adenocarcinoma is a malignant tumor arising from the malignant transformation of glandular epithelium. The treatment of adenocarcinoma varies with the type of adenocarcinoma. In general, surgery is the main treatment for early adenocarcinoma. Some adenocarcinomas require chemotherapy after surgery, and the chemotherapy regimen varies greatly from one adenocarcinoma to another, some adenocarcinomas are particularly suitable for targeted therapy, and the most representative one is lung adenocarcinoma. About 50% of patients with lung adenocarcinoma carry human epidermal growth factor receptor mutation gene, which has good therapeutic response to epidermal growth factor receptor tyrosine kinase inhibitors such as gefitinib and erlotinib, and can be the first choice of treatment, other methods include radiation therapy, physical ablation therapy, and Chinese herbal medicine treatment.