Treatment should be individualized according to the patient’s tumor stage. For the treatment of primary foci, radiotherapy, simple surgical resection or cryotherapy can be considered for early stage highly differentiated tongue cancer; for advanced stage, comprehensive treatment, i.e. “radiotherapy + surgery” or “chemotherapy + surgery + radiotherapy” should be adopted. For the treatment of metastases, due to the high rate of cervical lymph node metastasis in tongue cancer, selective cervical lymph node dissection should be considered at the same time except for stage T1.