Vague pain in the lower right side of the rib cage can be triggered by a variety of diseases, mainly liver and biliary diseases and chest wall diseases. The most common causes of pain in the lower right side of the rib cage are liver and biliary pathologies, such as gallbladder polyps, cholecystitis, gallbladder stones, viral hepatitis, liver stagnation, etc. Intercostal neuritis, herpes caused by varicella zoster virus, etc. can also cause pain; gastrointestinal diseases, such as pancreatitis, pancreatic cancer, gastric cancer, gastric ulcer, esophageal tumors, foreign body damage to the esophagus, etc. can also cause pain. Pain can also be caused by esophageal tumors and foreign body injuries in the esophagus; breast cancer can also cause pain; strenuous exercise, exertion, and chest crushing trauma can also cause pain; traumatic rib fractures can also cause pain, as can pleurisy of various causes. If you have pain in the lower right side of your ribs, we recommend that you go to the hospital for ultrasound and X-ray examinations and blood tests to determine what kind of disease is causing the pain. You should choose the right medication to treat the cause. You can also take analgesic drugs, hot physiotherapy, and local hormone treatment. It is important to take proper rest, reduce activities, avoid overexertion and do not eat spicy and stimulating food. In conclusion, there is a vague pain in the lower right side of the rib cage, which is caused by various reasons. It is recommended to go to the hospital for clear diagnosis and early treatment to avoid delaying the condition.