Clinically there is no rheumatoid factor, it is generally believed that rheumatoid factor is rheumatoid factor, there is no difference between the two. Rheumatoid factor is one kind of autoantibody, divided into lgA, lgG, lgE and other types, the antibody to denatured lgG as the target antigen, so it is also known as anti-antibody, the rheumatoid factor test is mainly for the diagnosis of rheumatoid arthritis, systemic lupus erythematosus, tuberculosis, chronic hepatitis and other diseases to provide a clinical reference basis. Rheumatoid factor should be detected in the morning on an empty stomach after blood sampling, rheumatoid factor test results alone can not confirm the diagnosis of the above diseases, rheumatoid factor test results should be abnormal patients should be further improved autoantibody profile, sedimentation, CRP, ultrasound and other ancillary tests in order to make a definitive diagnosis. It is recommended that patients who have questions about rheumatoid factor test to the rheumatology and immunology department of regular hospitals and other related departments for detailed consultation.