The abdominal pain from appendicitis can be mobile. In most clinical patients with acute appendicitis, the pain is early on in the upper abdomen or umbilicus, accompanied by distinct paroxysmal colic, and the pain is gradually increasing throughout the course of the disease, sometimes accompanied by a degree of nausea, which lasts for about 12 hours, and then the inflammation involves the mural peritoneum, so the pain gradually shifts to the right lower abdomen, and continues to increase. and continues to increase. In some patients, the nausea increases and vomiting occurs, and there are systemic symptoms such as fever due to the infection. In other patients, the pain is sometimes predominantly in the lower right abdomen at the beginning, but soon becomes severe in the whole abdomen, usually due to perforation of the appendix caused by complete obstruction of the appendiceal cavity by a fecal stone, and the pain may decrease momentarily in the middle of the perforation, which is sometimes mistaken for improvement and delays treatment.