Standard treatment of hyperuricemia

  1, low purine diet. Curb your gourmand desire, don’t drink, eat less meat, eat less seafood, eat more rice and noodles fine grains, vegetables should also be picked and eaten, if there is no diabetes, melon fruit pear peach can eat. You can also eat eggs. Will not have a great impact on the quality of life. If you can’t control your mouth, as always, eat well, if you get gout, that can really affect the quality of life.  2, adhere to the exercise, control weight. Of course, exercise should not be too strenuous, but also to play the role of exercise. The middle of everything is the best, the amount of activity to moderate intensity is better. Change the sedentary lifestyle, avoid overweight, already overweight or obese to lose weight. Valuable in persistence.  3, quit smoking and limit alcohol, ensure water. Smoking has many harmful effects, can quit must quit. Limit alcohol is very important, beer, white wine to prohibit, red wine low purine content, you can drink a little.  4, avoid the application of drugs that raise uric acid. Many drugs can affect the production or excretion of uric acid, such as thiazide diuretics, corticosteroids, insulin, aspirin, compound antihypertensive tablets, nifedipine, propranolol and other drugs, long-term application can cause an increase in uric acid. Therefore, when taking drugs, you should study the instructions carefully, and if they have adverse effects on uric acid, you should not use them if you can, or switch to other drugs. Of course, it is best to consult a professional doctor before stopping the use, so as not to affect the treatment of other diseases. If you have diabetes with very high blood sugar, or complications are very. Severe, it is dangerous to stop using insulin at risk.  5. Apply drugs that lower uric acid. One is the drug that increases uric acid excretion, commonly used drug is benzbromarone, the trade name is Ligarixian. The starting dose for adults is 50mg (1 tablet) once a day, and after 1-3 weeks the dose is adjusted according to the uric acid level, and can be increased to 2 tablets each time, taken after breakfast. Reduce the dose appropriately in the presence of renal insufficiency. Application of benzbromarone requires alkalinization of the urine and careful monitoring of liver and kidney function. Drugs that increase uric acid excretion can cause urate vigilance in the urinary tract and are a relative contraindication in patients with uric acid stones.  Alkalinize urine mostly with sodium bicarbonate, which can alkalinize urine, increase uric acid excretion and reduce the role of blood uric acid. The usual dosage is 3-6 grams per day, divided into 3 oral doses. Maintaining the urine PH between 6.2-6.9 is best to facilitate the dissolution of urate crystals and their excretion from the urine. Urine PH above 7.0 tends to form calcium oxalate and other types of stones.  Another drug that lowers uric acid works by inhibiting uric acid synthesis and is represented by allopurinol. The initial dose for adults is 50mg once, 1-2 times a day, which can be increased by 50-100mg per week to 200-300mg per day, divided into 2-3 oral doses. The maximum daily dose should not exceed 600 mg and should be reduced in cases of renal insufficiency.  It is important to note that allopurinol is commonly associated with allergic reactions. Mild allergy is usually manifested as a rash, which can be treated by desensitization, while severe allergy may result in delayed vasculitis, exfoliative dermatitis, etc. Serious cases may be life-threatening and require immediate discontinuation of the drug. The risk of severe allergy can be aggravated by renal insufficiency. Therefore, liver and kidney function and blood and urine routine should be monitored during the administration of allopurinol. Severe hepatic and renal insufficiency and marked hematocrit are contraindicated.