The best treatment for nephrotic syndrome depends on the type of renal pathology. If the type of renal pathology is microscopic, only glucocorticoid therapy is required, and in the case of membranous nephropathy, treatment with adequate doses of glucocorticoids combined with appropriate immunosuppressive agents. Prednisone or methylprednisolone is recommended for glucocorticoids, and the drug of choice for immunosuppression is cyclophosphamide; cyclosporine or tacrolimus may also be considered. In clinical practice, certain rare cases can also be considered with drugs such as ralston or leflunomide or azathioprine. Of course, these treatments require the exclusion of tuberculosis, infection, and other contraindications to glucocorticoid application. At the same time, symptomatic application of diuretic, decongestant, antihypertensive and anticoagulant therapy drugs such as furosemide, nifedipine extended-release tablets, valsartan or Bactrim, warfarin, etc. is required.