Cervical and lumbar disc herniation is a common and frequent disease. There are many methods in clinical treatment, such as acupuncture, massage, traction, lying on a hard bed, closure, plaster and so on. Although there is a certain degree of efficacy, but it is not easy to consolidate, easy to recur. Surgery is a means of radical treatment, but surgery is traumatic, surgery has a certain risk, most patients are not easy to accept. Ozone intervention in the treatment of herniated disc is a minimally invasive treatment in recent years, which is prevalent in some European countries. With its small damage, fast results, low cost, easy to be accepted by patients, by doctors and patients, the project is a fast and intuitive treatment of herniated disc is an effective method, mainly for disc bulging and herniation can be exempted from surgery, a needle treatment, the efficacy of the treatment is remarkable, has now become the first choice of patients with intervertebral disc herniation treatment program. The mechanism of ozone therapy 1, ozone is a strong oxidizing agent. It destroys the proteoglycans in the matrix of the nucleus pulposus, causing the nucleus pulposus to lose water and shrink, and relieving the pressure of the herniated nucleus pulposus on the nerve root. Ozone also destroys medullary cells, causing a decrease in the production and secretion of proteoglycans in the medulla. 2, experiments have confirmed that ozone can promote the dissipation of the inflammatory process, mainly through the following aspects: affecting the release of cytokine antagonists or self-immune inhibitory cytokines, such as IL210 and TGF β1; causing the over-expression of antioxidant enzymes in order to neutralize the excessive reactive products; stimulate the endothelial cells of blood vessels to produce NO and PDGF, causing vasodilatation, which leads to the dissipation of the inflammation. Clinical and experimental studies have shown that ozone can relieve pain in most patients with acute and chronic arthropathy and lower back syndrome. bocci believes that ozone injected through a puncture needle produces the so-called “chemical acupuncture” effect, which activates the inhibitory mechanism of pain perception and stimulates the release of enkephalins from the inhibitory interneurons to relieve pain. At the same time, ozone can also achieve analgesia by inhibiting the release of chemicals and promoting the dissipation of inflammatory processes. 4. Compared with other minimally invasive treatments for herniated disc, medical ozone intradiscal injection has its advantages. First of all, ozone is a very active chemical substance, which is injected into the intervertebral disc and paravertebral space very quickly. With a half-life of 20 minutes, it breaks down into O2 and O-, and the residual O- can be combined with each other to form O2, so there is no need to worry about the long-term residual ozone causing harm. Secondly, the treatment process only requires a 19-22G puncture needle, which is easy to operate and almost non-invasive, and requires no expensive equipment and medicines, and can be carried out in an outpatient clinic, which greatly reduces the cost of patients. The antibacterial and antiviral function of ozone can greatly reduce the chance of postoperative disc infection.