If there is edema in the eye, that is, edema in the eyelid, which is generally said by the common people to be a fire, there may actually be a more serious problem. If the eye is swollen unilaterally, it could be a local eye lesion, inflammation, trauma, allergy, and mosquito bites, which would require symptomatic treatment to eliminate the edema. If there is bilateral edema of the eyelid, it may be due to a local lesion, such as an eye lesion, local skin allergy to cosmetics, medications or food. If these conditions are ruled out, it may be a manifestation of systemic systemic pathology in the eyes, such as kidney disease, liver disease, heart disease, rheumatic system disease, and skin system disease such as allergic purpura. Each disease has unique characteristics and requires differential diagnosis based on different clinical manifestations, symptoms, signs, laboratory tests, and corresponding imaging examinations to be more beneficial in reducing swelling and pain. Once the cause is identified, treatment needs to be directed at the primary cause, and only when the primary cause is resolved will the eyelid edema and pain disappear accordingly.