Chronic kidney failure disease is not exclusive to adults, many children may also suffer from chronic kidney failure disease. If parents find that their children are unfortunately suffering from chronic kidney failure in children, they must remember the principle of “early detection and early treatment”. So, what are the symptoms of chronic kidney failure in children? Here we will follow the experts to understand the symptoms and performance of children with chronic kidney failure disease. Regarding the symptoms of chronic renal failure in children, the clinical symptoms of chronic renal failure in children may generally be characterized by frequent nausea and vomiting, poor sleep at night, lack of appetite, itchy skin, easy fatigue and edema, and in some cases, anemia and hematuria (urine appears tea-colored or blood-red) and hypertension. Digestive health problems can be the earliest and most common symptom of chronic kidney failure in children. Patients often have anorexia (loss of appetite is also an early symptom), sometimes nausea, vomiting and abdominal distention, and ulcers on the tongue and in the mouth. The patient’s mouth often smells of ammonia and the upper gastrointestinal tract often bleeds. These are the symptoms of chronic renal failure in children, and I hope they will be of help to the children and their parents. In addition, many children with chronic renal failure often have foam in their urine, and patients even have diarrhea, and sometimes children with chronic renal failure are often extremely thirsty or sleepy, sometimes drowsy, and have a decreased appetite. For patients with chronic renal failure, especially pediatric patients, early detection and early diagnosis and treatment is very important, as long as timely treatment, will certainly be effective.