The topical efficacy of aspirin, which some people believe has a cosmetic effect, is not reliable and has not been scientifically proven. In addition, the only clinical aspirin dosage forms are enteric tablets, bulk, suppositories, and effervescent tablets, and there are no topical dosage forms, so aspirin does not have topical efficacy. Aspirin is a traditional antipyretic and analgesic drug, mainly used to reduce fever in febrile diseases such as cold and flu, and also used to relieve mild to moderate pain symptoms such as toothache, headache, neuralgia, muscle aches and rheumatic pain. In addition, it also has an inhibitory effect on platelet agglutination, so it is often used clinically to prevent thrombosis. Aspirin can also be used for pain relief in acute and chronic rheumatic diseases, such as rheumatoid arthritis, idiopathic arthritis, osteoarthritis, and ankylosing spondylitis. In terms of antithrombotic effect, it is mainly used clinically in the early stages of cardiovascular diseases, such as angina pectoris, myocardial infarction or prevention of high-risk cardiovascular events, as well as in the treatment of cerebrovascular diseases such as stroke. The application of aspirin should be carried out under the guidance of a physician and should not be taken in excess to avoid salicylic acid reactions such as headache, dizziness, tinnitus, psychiatric disorders in children or gastrointestinal adverse reactions. In addition, it is not recommended to use the internal dosage form for external application by oneself to avoid skin allergy or other uncomfortable symptoms.