When there is inflammation around the teeth, it can be relieved and treated by taking metronidazole. Metronidazole is an anti-anaerobic drug, after taking it orally, some of the anaerobic bacteria around the teeth inside the mouth will be removed, which will be beneficial for periodontal inflammation. However, for periodontal inflammation, the most important approach is to take a localized treatment, also known as periodontal systemic therapy. You need to remove the bacteria and calculus around the teeth, take supragingival scaling and subgingival scraping, root planing and so on. If you simply take medication, the bacteria around the teeth can not be removed, and will not play a role in the complete treatment, but only to alleviate some of the symptoms.