Severe hypersplenism can lead to a decrease in peripheral blood trisomy and compression of the peripheral organs of the spleen. At present, hormone and reactive treatment are usually ineffective, and chemotherapy such as cyclophosphamide or radiotherapy to the spleen area is used later to shrink the spleen and relieve the symptoms caused by hypersplenism, but the side effects are large. We have developed a special formula for the treatment of hypersplenism by following the ancient formula and combining it with modern research on the mechanism of immune cell apoptosis – Spleen Elimination Soup.