Needle biopsy of thyroid nodules is usually a fine needle aspiration biopsy of thyroid nodules, which is the gold standard for the diagnosis of thyroid nodules, in which a fine needle is used to remove some of the tissue in the nodule for pathologic testing to determine the benign or malignant nature of the thyroid nodule. Generally before thyroid nodule puncture biopsy, lidocaine will be injected into the puncture site for local infiltration anesthesia. Thyroid nodule puncture is performed with a fine needle, which is minimally invasive and painless. A few patients may occasionally experience pain or bleeding, hematoma formation, nodal infarction, and infection after puncture. The most common complication is bleeding, because the thyroid gland is rich in blood flow, so it is necessary to make good preoperative preparations, and the patient should cooperate with the doctor during puncture, breathe calmly, and do not make swallowing motions, so as to avoid accidental injury to blood vessels. When a thyroid ultrasound is done and a thyroid nodule is found, if it is judged that the nodule has a certain risk of malignancy, it is usually recommended to do a needle biopsy of the thyroid nodule, and the specifics can be consulted with a specialized doctor.