When anemia occurs in diabetes, it is important to identify what the cause of the anemia is. This includes conditions caused by other systemic diseases in combination, or by diabetes itself, as well as by glucose-lowering medications. The primary cause of the disease and the type of anemia should be treated accordingly. 1.Actively treat the primary diseases that cause anemia, such as anti-infection, anti-tuberculosis, treatment of peptic ulcer and menstrual disorders. 2.Adjust the dietary structure and hypoglycemic drugs, increase the intake of protein and fresh vegetables appropriately. If it is determined that the anemia is related to taking certain hypoglycemic drugs, other hypoglycemic drugs or insulin should be used in time. 3.According to the different types of anemia, targeted treatment should be given. (1) Iron deficiency anemia Supplemental iron, ferrous succinate, or ferrous sulfate, 0.2-0.3g, oral, 3 times/day. Increase intake of animal liver, lean meat, animal blood products (e.g. duck blood), eggs, milk, black fungus, kelp, nori, shiitake mushrooms, beans. (2) Megaloblastic anemia Supplementation of vitamin B12 and folic acid, folic acid 5-10mg, 3 times/day; vitamin B12100ug, intramuscular injection, 1 time/day. Increase foods rich in folic acid and vitamin B12, such as meat, liver, egg yolk, green leafy vegetables, etc. in the diet as appropriate. (3) Renal anemia Erythropoietin (EPO) 80～120 U/kg (about 6000U) per week, subcutaneous injection in 2～3 times.