The effect of Gamma Knife treatment of cerebral vascular malformation is very good. However, we must pay attention to the fact that Gamma Knife is not the treatment program for all cerebral vascular malformations, and the effect is very good for relatively simple cerebral vascular malformations, such as small cerebral vascular malformations, the diameter of which is generally less than 3cm, so that the Gamma Knife penetration is relatively powerful, and the therapeutic effect is also very good. However, in clinical practice, cerebrovascular malformations are relatively large and require not only Gamma Knife treatment, but also interventional endovascular treatment and open surgical treatment. Gamma Knife radiation therapy is also required if there is an appropriate residual, and these are a variety of treatment modalities. For relatively small cerebrovascular malformations, a single treatment is basically sufficient, but for relatively complex ones, a combination of treatment modalities is required, which is more conducive to minimizing the patient’s suffering.