Patients with chronic renal failure must be treated with hemodialysis when any of the following characteristics occur: 1. blood CREA >707umol/L, 2. blood potassium >6.5mmol/L, 3. symptoms of cardiac insufficiency such as panic, shortness of breath, inability to sleep flat, 4. severe gastrointestinal reactions, bleeding tendency, etc., 5. other conditions. Blood creatinine is the waste produced by the body’s metabolism, and most of it is excreted by the kidneys. If there is serious kidney function damage, kidney replacement therapy (hemodialysis, peritoneal dialysis, kidney transplantation) is necessary to replace the function or part of the function of the normal kidneys and maintain human life. It is important to accept such treatment mentally and cooperate closely, which can lead to long-term survival of the patient. The longest dialysis patient has survived for more than 40 years. In addition to hemodialysis treatment, these patients must be given the following systematic treatment: 1. Effective blood pressure control: choose effective antihypertensive drugs for patients, mainly long-acting antihypertensive drugs, to ensure that blood pressure is controlled within the normal or near-normal range. 2, effective correction of anemia treatment: in addition to adequate erythropoietin (EPO), must be supplemented with sufficient iron, folic acid, vitamin B12 and other hematopoietic materials; 3, correction of renal bone disease: through the application of “osteotriol (rogaine)” to promote the absorption of calcium in the gastrointestinal tract, promote the absorption of calcium in the bones, to avoid osteoporosis. 4.Strengthen nutritional support therapy. 4, strengthen nutritional support treatment, can supplement the kidney essential amino acids, various vitamins, trace elements, etc., to avoid malnutrition. 5, diabetic nephropathy patients need to effectively control blood sugar.