Gastric mucosal congestion and edema is a microscopic manifestation of acute gastritis. Gastric mucosal congestion and edema can be seen during clinical gastroscopy. Congestion refers to localized redness of the gastric mucosa, and edema is a significant increase in the translucency or reflection of the gastric mucosa under the microscope. This kind of gastric mucosal manifestation is mostly seen in people with a history of alcohol consumption or smoking, as well as in people with H. pylori infection, people with irregular diet, and patients taking oral NSAIDs or cold medications. If this is the case, or even if there is significant upper abdominal pain and other discomfort, the use of gastric mucosal protectors or PPI inhibitors is recommended under the guidance of a specialized clinician. Most importantly, it is recommended to actively seek and remove the causative factors for early detection and treatment.