Patient: I had lung cancer in 2006, had 8 times of chemotherapy, and now it has become bone metastasis. How should this disease be treated? Shen Zhan, Department of Medical Oncology, Shanghai Sixth People’s Hospital: Lung cancer is divided into non-small cell lung cancer and small cell lung cancer, and the treatment principles for the two are completely different. Generally speaking, lung cancer is mostly non-small cell lung cancer, and surgery should be preferred for early stage of this kind of lung cancer. For progressive non-small cell carcinoma, chemotherapy is often preferred. You have not undergone surgery and used 8 times of chemotherapy, then you should be in the progressive stage, and now you have bone metastasis, which means that the previous chemotherapy can no longer control your disease. The following treatment should include two parts: 1. systemic treatment, such as chemotherapy or molecular targeted therapy with a different protocol; 2. local treatment for the site of bone metastasis, such as cementoplasty or local radiotherapy, this local treatment is important because Bone metastases can cause unbearable swelling and pain, fractures, and can even be life-threatening.