Cabozantinib is a multi-target anti-tumor drug, generally there are 1-3 tumor targets, while cabozantinib has more than 9 targets, mainly needle RET, ROS1 and other related targets. Cabozantinib can be used in many kinds of tumors, including lung cancer, liver cancer, thyroid cancer, etc. The use of cabozantinib in lung cancer treatment, generally through genetic testing, is not preferred to cabozantinib. Cabozantinib is not particularly used in clinical practice, Apatinib, Anrotinib, etc., are more used in China, and Cabozantinib is not available now. At this stage, people buy a lot of original powder, which is actually counterfeit drugs, the country said counterfeit drugs are actually generic drugs. Cabozantinib use process should be noted to have the occurrence of hand and foot syndrome, stomatitis, diarrhea, and common targeted drugs have the same side effects, for oral mucosa damage, damage to the intestinal tract, damage to the hands and feet, and the side effects of hypertension. Therefore, it is important to monitor blood pressure during the use of cabozantinib, and have the patient watch for any changes in the hands and feet, any pain in the mouth, and any diarrhea. If relevant symptoms appear, promptly tell the doctor, who will give symptomatic and early treatment.