Syphilis rash can occur on the face, trunk, limbs, palms, feet and other parts of the body. 1. Trunk: Syphilis rash on the trunk often appears as a densely distributed reddish blotchy rash or reddish maculopapular rash. 2. Face: Syphilis rash can appear on the face and is usually a macular or maculopapular rash. 3. Palms, feet and other parts of the body: syphilis rash can appear on the palms of the hands, feet and limbs, often symmetrically distributed, accompanied by collar-like flaking; syphilis rash can also appear in the genitals, perianal area. The clinical manifestations of the syphilis rash are varied, and can be macules, papules, tonoplast-like plaques or tonoplast-like structures, and some rashes can eventually develop into skin atrophy. With aggressive treatment of syphilis with penicillin as prescribed by the doctor, the skin lesions may gradually recede as the disease improves. If the patient has a history of unclean sexual intercourse and there are typical skin lesions, it may be the manifestation of syphilis, you need to timely medical examination and active treatment, do not delay the condition.