1. Familial adenomatous polyposis combined with pancreatic cancer is higher than the normal population. 2. Internal papillary mucinous neoplasm is also a precancerous lesion. 3.People with family history of pancreatic cancer, it is believed that genetic factors account for 5% to 10% in the development of pancreatic cancer. 4.Patients who are older than 40 years old and have non-specific symptoms in the upper abdomen. 5.High risk factors for pancreatic cancer include smoking, heavy alcohol consumption and long-term exposure to harmful chemicals. 6. The incidence of pancreatic cancer is 1.5 to 5 times higher in those who have undergone major distal gastrectomy for benign lesions, especially in those who are more than 20 years postoperative. 7.Patients with chronic pancreatitis, which is now considered to be an important precancerous lesion in some patients, especially chronic familial pancreatitis and chronic calcific pancreatitis. 8.Patients with sudden onset diabetes, especially atypical diabetes, age above 60 years, lack of family history, no obesity, and soon forming insulin resistance. 40% of pancreatic cancer patients have diabetes at the time of diagnosis.