There are three antibodies in Hepatitis B half-pair test, which are Hepatitis B surface antibody, Hepatitis B core antibody and Hepatitis B e antibody. Hepatitis B surface antibody is a kind of protective antibody, positive indicates that the body is resistant to hepatitis B virus; positive hepatitis B core antibody is a sign of early hepatitis B infection, and positive hepatitis B e antibody indicates that hepatitis B virus replication is not active. Hepatitis B virus is a spherical virus composed of envelope and nucleocapsid, and the envelope contains HBsAg, glycoprotein and other components. After the hepatitis B virus invades the human body, the immune system will produce substances to resist the virus. Hepatitis B surface antibody is one of the antibodies produced by the human immune system against the surface antigen of the hepatitis B virus, which is protective to our body, and it can bind with the surface antigen of the hepatitis B virus to play a role in resisting the invasion of the hepatitis B virus. Hepatitis B core antibody is the antibody corresponding to the core antigen of Hepatitis B virus, its presence indicates that the body has been infected with the Hepatitis B virus, but it cannot indicate other symptoms, so it has to be analyzed in conjunction with other test results. Hepatitis B e antibody positive means that hepatitis B virus is still infectious, very low or very little, suggesting that the body has been infected with hepatitis B virus for a long time. At present, the most important way to prevent hepatitis B is hepatitis B vaccination, the main component is hepatitis B surface antigen, after vaccination, the body’s immune system will also produce protective hepatitis B surface antibody, so that the human body has the immunity to prevent hepatitis B. At this time, hepatitis B penta-analysis only shows that the surface antibody is positive, and the hepatitis B indicates that the antigen, the core antibody and the e antibody are all negative.