Chronic superficial gastritis with gastric sinus erosion should be sent for biopsy. Gastric cancer mostly occurs in the side of the small curvature of the gastric sinus, chronic superficial gastritis and non-atrophic gastritis, accompanied by gastric sinus erosion need to take a pathological biopsy, biopsy not only can understand the existence of Helicobacter pylori infection, but also to see whether it is in the active stage and the type of pathology. If non-atrophic gastritis is asymptomatic, it can be observed and does not require medication for the time being. However, with erosion, regardless of whether there are symptoms or not, medication is needed (e.g., teprenone, omeprazole, etc.). With Helicobacter pylori infection, anti-Helicobacter pylori treatment is more needed, such as omeprazole, amoxicillin, bismuth potassium citrate, clarithromycin. Chronic superficial gastritis with gastric sinus erosion must be treated with medication as prescribed by the doctor, so as to avoid subsequent ulceration and bleeding.