Gallstones do not necessarily require removal of the gallbladder. Gallstones, as the most common benign disease of the hepatobiliary system, occur as a result of an imbalance in the dissolution of bile acids and cholesterol, or a bacterial infection of the biliary system, which is closely related. In clinical practice, the majority of gallbladder stones are treated by laparoscopic cholecystectomy for their eradication. However, with further research on gallstones, for single gallbladder stones with good gallbladder contraction, trans-laparoscopic removal of gallbladder stones and laparoscopic re-suturing of the gallbladder can be considered. Therefore, the treatment of gallstones does not necessarily involve the removal of the gallbladder, and biliary stone extraction therapy can be considered, provided that the stones are solitary and that the gallbladder is in normal contractile function.