Common symptoms 1, abdominal pain: abdominal pain is one of the main clinical manifestations of gallbladder stones. Gallbladder stone attacks mostly have the typical biliary colic. It is characterized by paroxysmal spasmodic pain in the upper abdomen or right upper abdomen with progressive aggravation, often radiating to the right shoulder and back. The abdominal pain is caused by stones moving from the gallbladder lumen to the cystic duct causing stone impaction. More than 90% of biliary colic is sudden and often occurs after a full meal, overexertion or strenuous exercise. Stones tend to fall into the cystic duct when lying down, and some patients have a sudden onset at night. In addition to severe pain, it is often accompanied by restlessness, even tossing and turning, distraction, sweating, and pallor. Each attack can last from 10 minutes to several hours, and it often takes several days for the attack to resolve. Pain relief or disappearance indicates that the stone has retreated into the gallbladder, at which time other symptoms disappear. 2. Gastrointestinal symptoms: In an acute attack of gallbladder stones, there are often gastrointestinal reactions such as nausea and vomiting following the abdominal pain. The vomit is mostly stomach contents, and the abdominal pain is not significantly relieved after vomiting. After the acute attack, there are often symptoms such as aversion to greasy food, abdominal distension and indigestion. 3. Fever and chills: Fever is related to the degree of inflammation of the gallbladder. Gangrenous cholecystitis and purulent cholecystitis may have chills and high fever. 4. Jaundice: Some patients with gallbladder stones can develop transient jaundice, mostly after severe abdominal pain, and the jaundice is mild. Gallbladder stones with cholangitis, enlarged gallbladder pressing on the common bile duct and causing partial obstruction, or transient damage to liver cells due to infection can cause jaundice. It is manifested as yellowing of the sclera of the eyes.