The choice of drugs for insomnia patients is divided into the following five categories: 1. choose melatonin or melatonin receptor agonists, mainly for elderly patients or jet lag, which can regulate the sleep-wake cycle of patients and have fewer side effects; 2. choose non-benzodiazepines, including zolpidem and dexrazopiclone, which are the drugs of choice for insomnia patients and have relatively few side effects and do not produce daytime sleepiness the next day; 3. The side effects are relatively small and do not produce daytime sleepiness the next day, and the half-life is relatively short; 3. Patients with chronic and severe insomnia can choose benzodiazepines, such as eszopiclone or alprazolam, which can reduce the time or number of awakenings and increase the total amount of sleep, but try to use them sparingly, because a large number of long-term use is prone to addiction dependence. If it is not a long-term, severe insomnia as little as possible, if it is a long-term use of such sedative-sleeping drugs, it is recommended not to use continuous medication, it is best to intermittent or on-demand medication; 4, with anxiety and depression of insomnia patients, can be given with sedative-sleeping type of anti-anxiety and depression drugs, such as small doses of amitriptyline or doxepin; 5, if it is a long-term serious insomnia, conventional treatment are unable to relieve. It is recommended to go to a mental health center or insomnia clinic for further diagnosis and treatment.