Blunted renal calyces is a clinical manifestation of nail-patellar syndrome and one of its complications. The following are the symptoms of nail-patella syndrome, which patients with nail-patella blunting should know more about! Nail-patella syndrome or hereditary bone-finger (toe) nail dystrophy is a genetic disorder characterized by patellar hypoplasia or absence, finger (toe) nail dystrophy, elbow dysplasia, iliac angle and renal failure. 1897 Little first described this disease. mid 1960s Muth and Silverman described lesions in the glomerular structure of this syndrome In the late 1960s and early 1970s Hoyer and Bennett began a comprehensive study of the ultrastructure of the glomerular basement membrane and renal pathological features of this syndrome, proposing a modern theory of the structural basis of the nail-patellar syndrome renal lesions and suggesting that the syndrome may be due to basement membrane biochemical defects of collagen.