The hepatopancreatic jugular is located in the descending duodenum, where the common bile duct and pancreatic duct converge and open into the duodenum, and is the opening for the drainage of bile and pancreatic juice into the intestine. The hepatopancreatic jugular lesion will cause obstruction of bile drainage and pancreatic fluid, and the patient will also experience epigastric pain, nausea, vomiting and fever. Severe cases of obstructive jaundice, most commonly caused by malignant tumors, may result in weight loss, abdominal pain, and weight loss, and in advanced cases may be complicated by massive ascites formation. Patients with early diagnosis should opt for surgical treatment, which requires combined pancreatic head and duodenal resection and is relatively invasive. Postoperative care should also be taken to prevent infection and intravenous nutritional support, as it involves reanastomosis of the common bile duct, which is also prone to the occurrence of biliary or pancreatic fistula.