The main signs of spinal consumption, one of the manifestations of spinal syphilis, are loss of knee and ankle reflexes, impaired vibration and position sensation in the lower extremities, and a positive closed-eye refractory sign. The central infection of syphilis begins with syphilitic meningitis (about 1/4 of all syphilitic infections), a large proportion of which is asymptomatic meningitis that can only be detected by lumbar puncture, and a small proportion of which manifests as a more severe meningitis dominated by cerebral nerve palsy, epilepsy, and increased intracranial pressure. Syphilitic meningitis can go through an asymptomatic phase for several years and eventually enter the phase of brain or spinal cord parenchymal involvement, which includes meningeal vascular syphilis, paralytic dementia, spinal cord consumption, and syphilitic spinal myelitis. How can we effectively prevent impaired vibration and position sensation in the lower extremities? We know that all central infections of syphilis begin with syphilitic meningitis, a large proportion of which is asymptomatic. If this early asymptomatic syphilitic infection is detected by lumbar puncture and treated appropriately, all kinds of central syphilis will be prevented. Conversely, if left untreated or improperly treated, asymptomatic syphilis meningitis will develop into meningeal vascular syphilis, paralytic dementia, and spinal consumption. Penicillin is the treatment of choice for all types of central syphilis (both symptomatic and asymptomatic). The dosage is 6-10 million U of penicillin per day, divided into intramuscular injections, 20 days as a course of treatment. Erythromycin 500mg 4 times/d for 30 days may be used for those allergic to penicillin. Treatment with penicillin may result in a first-dose reaction, manifested as a mild increase in body temperature and leukocytosis, which is generally uneventful. Some symptoms of neurosyphilis may not respond to penicillin treatment, especially spinal consumption, thus requiring the addition of other drugs. Phenytoin (phenytoin sodium) or carbamazepine may be used for lightning-like pain, and analgesics may also be used, but opioids must be avoided. Atropine and derivatives of phenothiazine are effective for visceral crisis. Treatment is usually repeated every 3 months and the cerebrospinal fluid is rechecked every 6 months until the cerebrospinal fluid cell count, protein content, and VDRL return to normal. The prognosis of spinal syphilis is uncertain, but most patients show some degree of improvement or at least quiescence, with a small percentage remaining mildly progressive after treatment has been initiated.